Articles - Clinical Trials en-us http://www.thescizone.com/info N/A http://www.thescizone.com/info webmaster@thescizone.com 20 http://www.thescizone.com/info/articles/479/1/TREADMILL-TRAINING/1.html Many aggressive rehabilitation programs have incorporated body-weight-supported (BWS) treadmill training to enhance ambulatory ability after spinal cord injury. This training apparently develops new function-restoring neuronal networks and triggers the spinal-cord’s “central-pattern generator,” a sort of brain within the spinal cord that can sustain lower-limb repetitive movement, such as walking, independent of direct brain control. The article summarizes various research studies evaluating the impact of treadmill training. Because specific procedures often vary considerably, it is hard to over-generalize the results. Some studies suggest considerable benefits, and others do not. webmaster@thescizone.com (Super Admin) Mon, 02 Apr 2007 00:00:00 -0400 http://www.thescizone.com/info/articles/476/1/Survey-of-Pain-and-Fatigue-in-Adults-with-Disabilities/1.html NOW RECRUITING - Announcing a new study of pain and fatigue in adults with multiple sclerosis and spinal cord injury.Pain and fatigue are the most common patient-reported symptoms cutting across a broad range of chronic diseases and conditions. They often occur together, yet the association has not been adequately studied and understood, and we lack adequate knowledge about the longitudinal patterns of pain and fatigue. The specific aims of this project are: 1) to develop a psychometrically validated instrument or battery of instruments for measuring pain, fatigue, social participation, emotional distress, and physical functioning in persons with disabilities; 2) to improve current measures of patient-reported outcomes; and 3) to increase scientific understanding of the course of pain and fatigue and their associations with important outcome measures including depression, participation, and disability level. Our primary hypothesis is that both pain and fatigue will be significantly associated with participation, contributing above and beyond the effects of depression and disability. We also expect the magnitude of the effect to differ depending on medical diagnosis (multiple sclerosis (MS) or spinal cord injury (SCI). The proposed study involves two phases:(1) one initial survey of 1000 individuals with MS and SCI (500 of each); and (2) five follow-up surveys at four month intervals of 300 individuals from the initial survey. webmaster@thescizone.com (Super Admin) Mon, 29 Jan 2007 00:00:00 -0500 http://www.thescizone.com/info/articles/472/1/Levitra-vardenafil-HCl-Demonstrates-Normal-Erectile-Function-in-53-of-Men-with-Spinal-Cord-Injury-SCI/1.html “The label change and study results are very encouraging for the many men who suffer from spinal cord injury. The recorded levels of improvement in erectile function and ejaculation rates during the study period were impressive. This is great news for men suffering with ED resulting from spinal cord injury who wish to father children.” Lead author of the study, François Giuliano, MD, PhD, a professor at the department of urology, CHU de Bicetre, in Paris webmaster@thescizone.com (Super Admin) Wed, 03 Jan 2007 00:00:00 -0500 http://www.thescizone.com/info/articles/374/1/Spinal-Cord-Injury-Volunteers-are-Needed/Page-1.html The Translational Pain Research Group at the Brigham and Women's Hospital is conducting clinical trials that evaluate various medications to help relieve chronic neuropathic pain as a result of a Spinal Cord Injury. You may be eligible if you are: 18-70 years old Have been diagnosed with a Spinal Cord Injury Have had chronic neuropathic pain for at least 3 months For more information call 1-617-525-PAIN (7246) or email us at paintrials@partners.org. webmaster@thescizone.com (Super Admin) Sun, 06 Nov 2005 00:00:00 -0500 http://www.thescizone.com/info/articles/252/1/Clinical-Trials-Studies--Research-Surveys/Page-1.html Clinical Trials, Studies & Research Surveys webmaster@thescizone.com (Super Admin) Thu, 22 Sep 2005 00:00:00 -0400 http://www.thescizone.com/info/articles/203/1/Preclinical-And-Clinical-Testing-Of-New-Therapies/Page-1.html  Researchers have identified a wide variety of potential therapies for spinal cord injury. To efficiently evaluate these therapies, however, investigators need to carry out well-designed preclinical and clinical trials that will reveal the benefits and drawbacks of each strategy. webmaster@thescizone.com (Super Admin) Thu, 01 Apr 2004 00:00:00 -0500 http://www.thescizone.com/info/articles/200/1/Research-In-Sci-Treatment/Page-1.html  Hope lies, therefore, in treatments that could prevent these stages of progressive damage. Drugs that protect nerve cells following injury are now available to lessen the severity of some injuries. Other drugs and combinations of drugs are currently being tested in both animal and clinical trials. webmaster@thescizone.com (Super Admin) Sun, 14 Sep 2003 00:00:00 -0400 http://www.thescizone.com/info/articles/241/1/Craig-Hospital-to-launch-experimental-spine-therapy/Page-1.html An experimental therapy that has shown promise for people with spinal cord injuries will soon be available in the metro area. The process, called activated macrophage, has previously only been performed in Israel. That's where two young people from Colorado received it in an early test involving only 11 subjects. But Craig Hospital in Englewood is waiting for final approval from the Food and Drug Administration to bring activated macrophage to North America. It would be available to about 170 patients. Macrophage involves the isolation of white blood cells from bone marrow. They're combined with a graft of the patient's skin to activate the white blood cells' healing properties. The cells are then injected into the damaged area of the spinal cord within two weeks of injury. Patients who have benefited from the treatment have regained some feeling and use of their legs. webmaster@thescizone.com (Super Admin) Tue, 18 Mar 2003 00:00:00 -0500